Paul's political action committee, RandPAC, announced plans by the Kentucky senator and potential 2016 presidential candidate to file a class-action challenge on Wednesday.
The suit also will name National Intelligence Director James Clapper, outgoing NSA Director Keith Alexander, and FBI Director James Comey.
A firebrand in the Republican Party whose brand of conservatism embraces Libertarian ideals, Paul is an ardent critic of U.S. surveillance programs, which he says infringe on basic civil liberties under the Constitution.
"The Bill of Rights protects all citizens from general warrants. I expect this case to go all the way to the Supreme Court and I predict the American people will win," Paul said in a statement.