The American actor was quoted as saying by promoters: "Boxing is a serious part of my life. It taught me respect and determination, patience and concentration. I always dreamed of fighting a match in Russia."
Rourke is set to fight 29-year-old Elliot Seymour on November 28. They will take to the ring ahead of a match between Russia's Ruslan Provodnikov and Jose Luis Castillo of Mexico, Sovetsky Sport reported.
The actor was an amateur boxer before his Hollywood career took off and he became a sex symbol star in films such as "9 1/2 Weeks."
He returned to boxing as a professional for eight matches in the 1990s, causing damage to his face that necessitated surgery and changed his appearance.