A pioneering new stem cell treatment is reversing and then halting the potentially crippling effects of multiple sclerosis.
Patients embarking on a ground-breaking trial of the new treatment have found they can walk again and that the disease even appears to be stopped in its tracks.
"I started seeing changes within days of the stem cells being put in. It was a miracle"
Patient Holly Drewry
Holly Drewry, 25, from Sheffield, who was wheelchair bound after the birth of her daughter Isla, now two.
But Miss Drewry claims the new treatment has transformed her life.
She told the BBC's Panorama programme: "I couldn't walk steadily. I couldn't trust myself holding her (Isla) in case I fell. Being a new mum I wanted to do it all properly but my MS was stopping me from doing it.
"It is scary because you think, when is it going to end?"
The treatment is being carried out at Royal Hallamshire Hospital in Sheffield and Kings College Hospital, London and involves use a high dose of chemotherapy to knock out the immune system before rebuilding it with stem cells taken from the patient's own blood.
Miss Drewry had the treatment in Sheffield. She said: "I started seeing changes within days of the stem cells being put in.
"I walked out of the hospital. I walked into my house and hugged Isla. I cried and cried. It was a bit overwhelming. It was a miracle."
Her treatment has now been reviewed and her condition found to have been dramatically halted. She will need to be monitored for years but the hope is that her transplant will be a permanent fix.