In the US, that means a 2/3 approval by the Senate, followed by an official signing of the treaty by the President.

However, the schedule to allow stakeholder (NGO) and other input on a proposed pandemic treaty has apparently fallen under the guillotine, as the WHO is cancelling the second round of public input, scheduled for June 16-17.

As of today, this appeared on the webpage for the Intergovernmental Negotiating Body, which was established by the WHO in late 2021 to facilitate the drafting of a pandemic treaty.