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Studies See Advances in Detecting, Treating Pancreatic Cancer

•, By Alan Mozes

On the treatment front, researchers from two Cleveland institutions said they have fashioned a vaccine that, in early trials, appears to kick-start the patient's immune system into attacking cancer cells.

The team -- from Case Western Reserve University School of Medicine and the Seidman Cancer Center at University Hospitals Case Medical Center in Cleveland -- stressed that the vaccine (called Algenpantucel-L) is not designed to prevent disease from occurring in the first place.

Initial testing, however, indicates that when used in conjunction with a standard six months of chemotherapy (with or without radiation) and surgical interventions, the vaccine may prolong short-term, disease-free survival, and perhaps even overall survival.

Lynn Matrisian, vice president of scientific and medical affairs at the Pancreatic Cancer Action Network, said the vaccine work shows promise.

"We are eager for the outcome of the phase III trial of the Algenpantucel-L vaccine," she said. "The phase II results are very encouraging, and the ongoing larger-scale, randomized phase III trial will determine the effectiveness of this novel treatment strategy." 

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