The team, led by McGill professors John White and David Goltzman, of the Faculty of Medicine’s Department of Physiology, discovered that the active form of vitamin D acts by several mechanisms to inhibit both the production and function of the protein cMYC. cMYC drives cell division and is active at elevated levels in more than half of all cancers. Their results are published in the latest edition of Proceedings of the National Academy of Sciences.
For the past several years, there has been considerable interest in the role vitamin D plays in improving health and preventing disease. Previous finding show that low levels of vitamin D have been directly associated with various forms of cancer and cardiovascular disease. Stephen B. Kritchevsky, PhD, Professor of Internal Medicine and Transitional Science at the Wake Forest School of Medicine found a signficant correlation.
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