Whitaker is resigning from the network, according to a report from Alex Weprin at MediaBistro. In his outgoing memo to staff, Whitaker said he would depart because he believes incoming president Jeff Zucker "deserves his own team and management structure and the freedom to communicate one clear vision to the staff."

Meanwhile, political pundit couple James Carville and Mary Matalin will not have their contracts continued, according to Rothstein's report. And conservative contributor Erick Erickson will also leave the network for Fox News. Finally, the former Republican Secretary of Education Bill Bennett and Democratic strategist Maria Cardona are also not coming back. Cardona will remain a contributor with CNN Espanol.

The network has undergone a flurry of changes in the past month-plus. On Tuesday, the network also announced it was adding former ABC reporter and 20/20 co-anchor Chris Cuomo. In December, former ABC reporter and White House correspondent Jake Tapper joined the network.