Irradiation of liver cancer cells (hepatoma) with the same type of radiation used to treat cancer patients resulted in enriching the highly malignant cancer stem cell subpopulations, as well as cell properties associated with increased invasiveness and treatment resistance. [see figure 1 below]
The addition of pterostilbene, a stilbenoid chemically related to resveratrol and found in blueberries and grapes, suppressed the adverse changes associated with irradiation.
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