Non-prescribed over the counter (OTC) pharmaceutical pain killers also have side-effects. Some, such as Tylenol, contain acetaminophen, which is a toxic liver killer. Ibuprofen OTC products are NSAIDs (non-steroid anti-inflammatory drugs). Their side-effects may not be as dramatic as acetaminophen's, but they do produce gastrointestinal problems if used often.
Unless the pain is acutely severe, it's best to look into herbs that have been used traditionally for relieving pain and/or inflammation. In addition to the pain relief, herbs offer healing effects not offered by pharmaceuticals, which usually host several adverse side-effects.