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News Link • Science, Medicine and Technology

Israeli scientists discover substance that may fend off Alzheimer's, aging

•, By Ido Efrati
 According to the Hebrew University researchers, who tested the new material on worms, this is the first substance that shows potential to treat or prevent diseases like Alzheimer’s, Parkinson’s and Huntington’s.

The findings of the study, funded by the British Rosetrees Trust, and published recently in the journal Aging Cell, reinforces the claim that blocking the signaling pathway of insulin and the growth hormone IGF1, a pathway known to be a central controller of the aging process in worms and mammals, can potentially be used as a treatment for degenerative brain diseases, said the researchers, led by Dr. Ehud Cohen of Hebrew University’s Faculty of Medicine. The new findings are the first evidence that a pharmacological substance can effectively protect against toxicity of proteins associated with neurodegenerative diseases, through selective inhibition of the aging process, they said. The researchers have registered a patent for their discovery.

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