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News Link • Science, Medicine and Technology

Bioengineered human livers mimic natural development

• sciencedaily.com

Cincinnati Children's Hospital Medical Center

Summary:

Researchers bioengineering human liver tissues uncovered previously unknown networks of genetic-molecular crosstalk that control the organ's developmental processes -- greatly advancing efforts to generate healthy and usable human liver tissue from human pluripotent stem cells. The scientists report that their bioengineered human liver tissues still need additional rounds of molecular fine tuning before they can be tested in clinical trials.

An international team of researchers bioengineering human liver tissues uncovered previously unknown networks of genetic-molecular crosstalk that control the organ's developmental processes -- greatly advancing efforts to generate healthy and usable human liver tissue from human pluripotent stem cells.

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