The key to human regeneration is from week 3 to week 8 after fertilization of the egg when we are an embryo. In week one and week two, we are a zygote. After week, we are fetus.
Nextbigfuture will follow up this article with several more articles with information from the interview. This article will provide the core of the AgeX approach to full regeneration and radical life extension.
We fully regenerate without scarring from week three to week 8 as embryos but heal with scarring from week 9 onwards
All vertebrate embryos can regenerate the developing limb bud as embryos. This has been demonstrated directly in frog embryos, where it is relatively easy to do the surgical manipulations. In chick embryos, an amputated limb bud fails to regenerate because the epidermal covering fails to reform. If you graft a new apical epidermis, or provide the appropriate chemical signals that the epidermis normally produces (fibroblast growth factor), then the amputated limb bud will regenerate.