Previously, he was the member of the United States House of Representatives for Kansas's 4th congressional district (2011–17). He is a member of the Tea Party movement within the Republican Party. He was a Kansas representative on the Republican National Committee and member of the Italian American Congressional Delegation.
On March 13, 2018, Trump announced his intention to nominate Pompeo as the new United States Secretary of State, succeeding Rex Tillerson after March 31, 2018.
Pompeo was born in Orange, California, the son of Dorothy (née Mercer) and Wayne Pompeo. His father was of Italian ancestry. His paternal grandmother was born in Caramanico Terme. In 1982, Pompeo graduated from Los Amigos High School in Fountain Valley, California, where he played power forward on the basketball team. In 1986, Pompeo graduated first in his class from the United States Military Academy at West Point where he majored in Mechanical Engineering.
From 1986 to 1991, Pompeo served in the U.S. Army as an Armor Branch Cavalry Officer, reaching the rank of Captain.He served as a United States Cavalry officer patrolling the Iron Curtain before the fall of the Berlin Wall. He also served with the 2nd Squadron, 7th Cavalry in the 4th Infantry Division in the Gulf War.