Boehner released a statement Wednesday on Twitter saying that his "thinking on cannabis has evolved."
"I'm convinced de-scheduling the drug is needed so we can do research, help our veterans, and reverse the opioid epidemic ravaging our communities," Boehner said.
Acreage Holdings is one of the nation's largest cannabis corporations.
Boehner will also be joined on the Board of Advisors by former Massachusetts Gov. Bill Weld, who won the Libertarian nomination for vice president in 2016.
In a joint statement, the pair said they are hoping to to de-schedule cannabis from a Class 1 drug at the federal level so it can be used for medical purposes.