They are trying to develop lighter and longer-lasting batteries and fuel cells, advanced adhesives, coatings and paints and less expensive explosives that are safer to handle.
DARPA's Make-It program is in year three of a four-year program.
Make-It is achieving success due to its multidisciplinary focus with a talented group of researchers, combining computer science, organic chemistry, and chemical engineering expertise to address three areas: automated molecule design; automated synthesis, or production; and rapid reaction screening.
MIT, SRI International, and Grzybowski Scientific Inventions (GSI) are exploring different approaches for developing software to automatically design various chemical route options. GSI's molecular route optimization software is now commercially available.