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News Link • Science, Medicine and Technology

Early results boost hopes for historic gene editing attempt

•, by Marilynn Marchione

The results announced Wednesday are from the first human test of gene editing in the body, an attempt to permanently change someone's DNA to cure a disease — in this case, a genetic disorder called Hunter syndrome that often kills people in their teens.

In two patients who got a medium dose of the treatment, urine levels of large sugar compounds that are hallmarks of Hunter syndrome had fallen by half, on average, four months later — a possible sign the treatment is working. Two others who got a low dose have seen little change in these sugars so far.

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