Speaking at Community of Latin American and Caribbean States (CELAC) summit, a 33-country bloc conference without the presence of Canada and the U.S., Castro said the ongoing normalizing relations will be "meaningless" if the U.S. interferes in Cuban affairs.

Castro identified three conditions that will improve U.S. and Cuba relations. The first condition is lifting the U.S. embargo on Cuba, which only Congress can do. Second, Castro wants compensation for the "human and economic damage" the Cuban population suffered. Finally, Castro wants the U.S. Guantanamo Bay base returned to Cuban control.

"If these problems are not resolved, this diplomatic rapprochement between Cuba and the United States would be meaningless," he said.