In speaking with CBS News, Gates said, "None of the vaccines at this point appear like they'll work with a single dose," adding that in order to wipe the virus out through universal vaccinations it will require "unbelievably big numbers" of doses. To be effective, he also predicts we will need to vaccinate around 80% of the global population so, yes, we're talking about tens of billions of doses.

100% of Moderna Vaccine Participants Suffered Side Effects

Gates visibly struggles to maneuver through the pointed questions posed by CBS about the safety of the Moderna COVID-19 vaccine (currently known only as mRNA-1273), which was recently found2 to cause systemic side effects in 80% of Phase 1 participants receiving the 100 microgram (mcg) dose.
 

Side effects ranged from fatigue (80%), chills (80%), headache (60%) and myalgia or muscle pain (53%). After the second dose, 100% of participants in the 100-mcg group experienced side effects.