The federal mandate affected 280,000 teachers, staff, and volunteers with the Head Start program who were met with a "job-or-jab" ultimatum.

Judge Terry A. Doughty, an appointee of former President Donald Trump, opened his 27-page opinion quoting James Madison's Federalist No. 51, "The accumulation of all powers, legislative, executive, and judiciary, in the same hands, whether of one, a few, or many, and whether hereditary, self-appointed, or elected may justly be pronounced the very definition of tyranny." Doughty wrote:

The public interest is served by maintaining the constitutional structure and maintaining the liberty of individuals who do not want to take the COVID-19 vaccine. This interest outweighs Agency Defendants' interests. The public has a liberty interest in not being required to take a vaccine or be fired from their jobs. The public interest must be taken into account before allowing Agency Defendants to mandate vaccines.

The Biden administration required the vaccines and masks as part of its package of coronavirus-related mandates that included the vaccine mandate on private employers that was eventually blocked by the U.S. Supreme Court in NFIB v. OSHA.

In the Head Start case, staff and volunteers with the program were required to be vaccinated against the coronavirus by January 31, 2022, and all persons aged two years or older were required to wear masks.

"After initially rejecting vaccine mandates, President Joe Biden's 'patience' began 'wearing thin' with those 'who haven't gotten vaccinated,'" Doughty recalled in his review of the case's background.

After the mandates came down, Louisiana preschool teacher Sandy Brick — who serves Head Start students — filed the lawsuit to prevent her from either being vaccinated or fired from her job.

Brick is being represented by the Liberty Justice Center and the Pelican Institute for Public Policy.

In a press release, Pelican Institute general counsel Sarah Harbison said, "Louisiana teacher Sandy Brick has been serving her students through adversity and uncertainty the last two years. Today, this decision vindicates her right to teach without sacrificing her freedom."