A lucky California ticketholder struck the second-highest ever Powerball jackpot of $1.73 billion on Wednesday night.

The life-changing single ticket was sold at Midway Market & Liquor in Frazier Park, a community nestled inside the Los Padres National Forest – just over an hour from Los Angeles. 

The winning numbers were: 22, 24, 40, 52, 64 and the Powerball 10.

After 12 weeks of rollovers, the prize signals the end a long stretch without a winner. 

The whopping jackpot is the world´s second-largest lottery prize beaten only by the $2.04 billion Powerball prize won by Edwin Castro in California last November. 

Castro - who opted to take a lump sum of $997.6 million - has since purchased a $47 million Los Angeles compound, sold by celebrity realtor Mauricio Umansky, along with three separate California mansions for a total of $76 million.

The massive LA property has seven bedrooms and 11 bathrooms, a koi pond and an enormous infinity pool overlooking the city.

He was also seen driving away from a bank in a vintage Porsche.

Prior to Wednesday's draw another California player matched all six numbers and pocketed $1.08 billion on July 19. 

If Wednesday's winner choses to accept their prize as a lump sum they will be penalized more than any other in the last two decades.

When somebody wins the lottery they generally have two options as to how they can claim their prize money.

Either they accept a lump sum, which is paid to them immediately, or they claim the full 'headline' jackpot amount, which will be paid to them in annuities over the next 30 years.