One day after the FAA issued a Notice to Air Missions (NOTAM), or an alert notifying pilots of potential serious hazards in certain airspace, for the Maiquetía Flight Information Region above Venezula, Reuters reported that the US is poised to launch a new phase of Venezuela-related operations in the coming days, citing four U.S. officials.

Amid a sharp escalation of pressure by the Trump administration on President Nicolas Maduro's government, including proliferating reports of looming action as the US military deployed forces to the Caribbean amid worsening relations with Venezuela, two of the sources said covert operations would likely be the first part of the new action against Maduro, while two US officials told Reuters the options under consideration included attempting to overthrow Maduro.

A senior administration official on Saturday told Reuters that nothing had been ruled out regarding Venezuela.

"President Trump is prepared to use every element of American power to stop drugs from flooding into our country and to bring those responsible to justice," said the official, speaking on the condition of anonymity.

Before the Reuters report, six airlines had already cancelled flights to Venezuela on Saturday after the US aviation regulator warned major airlines of dangers from "heightened military activity" amid a major buildup of American forces in the region, as well as a "potentially hazardous situation" when flying over Venezuela and urged them to exercise caution.

Spain's Iberia, Portugal's TAP, Chile's LATAM, Colombia's Avianca, Brazil's GOL and Trinidad and Tobago's Caribbean have suspended their flights to the country, said Marisela de Loaiza, president of the Venezuelan Airlines Association (ALAV). Panama's Copa Airlines, Spain's Air Europa and PlusUltra, Turkish Airlines, and Venezuela's LASER are continuing to operate flights for now.

The Trump administration has been weighing Venezuela-related options to combat what it has portrayed as Maduro's role in supplying illegal drugs that have killed Americans. He has denied having any links to the illegal drug trade. 

Maduro, under whose rule Venezuela has experienced crushing hyperinflation and a collapse in its oil production sector amid staggering corruption, has contended that Trump seeks to oust him and that Venezuelan citizens and the military will resist any such attempt. He also has characterized U.S. actions as an effort to take control of Venezuela's oil.