The actual decline in function with age occur at the cell, organ, and systemic levels, but the impacts of this decline can differ with the individual's genes and environment. The net result of aging in an animal population is a progressive increase in all-cause mortality and morbidity. In the case of humans, all-cause mortality is known to double every eight years after sexual maturity until it reaches an annual mortality rate plateau of about 50% over 105 years of age.
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