"The Bushes are all tangled up with [DeSantis]," Simone said during a segment on Fox News Saturday.

"Bush who can raise him a billion dollars," Simone continued, adding that "Karl Rove will be the coach on the field, I think he's been advising him."

"That's why DeSantis has been getting a little better every week. They're all very smart," Simone further stated, adding "You saw what they did for Jeb Bush."

However, when it comes to taking on Trump, Simone noted that "I don't think they're ready for Donald Trump."

The claim prompted Trump's son Don Jr. to label DeSantis "a Trojan Horse for the RINO establishment."