Now that the bill has advanced, it will be followed by a Democrat-demand to read the entire 1,000-page bill on the floor (total children) before a maximum 20 hours of debate on the legislation and a multi-hour vote-o-rama, putting it on course for final passage from Sunday into Monday.

Two Republicans voted against the bill; Sen. Rand Paul (R-KY) - who opposed raising the debt ceiling by $5 trillion, and Thom Tillis (R-NC), who says the 'Big Beautiful Bill' could cost his state heavily when it comes to Medicaid funding.

Sen. Ron Johnson (R-WI) flipped his vote from "no" to "aye," while Sens. Mike Lee (UT), Rick Scott (FL) and Cynthia Lummis (WY) also voted yes. 

There was drama into the home stretch... less than an hour after the vote opened up, Sens. Lisa Murkowski (R-AK), Lee, and Scott, hadn't made an appearance on the Senate floor. Paul and Tillis had previously announced that they would oppose the motion to proceed, and could not support the bill in its current form. 

When Murkowski finally sauntered onto the floor, Thune quickly approached her along with Sens. Barrasso, Graham, and Senate Finance Committee Chairman Mike Crapo (R-ID), who peppered her with demands - as one does when it comes to Lisa Murkowski...

Update (1718ET): Elon Musk has weighed in on the Senate's latest iteration of President Trump's tax and spending bill, calling it "utterly insane and destructive," and that it will "destroy millions of jobs in America and cause immense strategic harm to our country!"

Musk also called it 'political suicide.'

Meanwhile, Senate Republicans are marching toward an initial vote Saturday afternoon despite several GOP Senators expressing grave concerns. 

Both Sens. Susan Collins (Maine) and Thom Tillis (North Carolina) are either "leaning against" or "no" on final passage. According to Politico, Trump "has personally reached out to Tillis to try to work him on the bill."

If at least two other Republicans join Tillis to oppose the procedural vote Saturday afternoon, Senate leadership would have to rely on Vice President JD Vance to break a tie to move forward to debate the bill. Sens. Rand Paul (R-Ky.), Ron Johnson (R-Wis.), Mike Lee (R-Utah) and Tim Sheehy (R-Mont.) all have concerns that could drive them to vote against moving forward.

Johnson and Paul, who have been vocally opposed to the bill because of its impact on the national debt, met with the president on Saturday shortly before the vote, according to Lee.

According to Sen. Markwayne Mullin (R-OK), "We won't bring it to the floor if we don't have the votes," adding "I think it'd be better to have the vice president close. I don't know if we're going to need him."