The junior senator from Kentucky railed against the "unholy alliance" in Washington, D.C., between the establishment of both parties he said has resulted in out-of-control domestic and military spending.

"Washington is horribly broken and you ask yourself whose fault is it. Well let's see, Republicans, Democrats — let's just say everybody in Washington ought to come home and we ought to start over," Paul said.

Seeking to distinguish himself from the 2016 field, Paul hit politicians of both parties for being too quick to entangle the U.S. in overseas conflicts.

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"If you're eager for war there's 10 other people I can recommend. If you're eager for war there will always be a Bush or Clinton for you," he said.