"If you get indicted, will you drop out?" he asked her.

The former secretary of state refused to answer the question.

"Oh, for goodness," she started when Ramos pressed her on the issue after she initially danced around it. "It's not going to happen. I'm not even answering that question."

The FBI has been looking into whether any classified material was mishandled during Clinton's tenure at the State Department from 2009 to 2013. The agency has said, however, that she is not a target in the investigation.

The debate exchange started when Ramos said that, by directing her staff to use official government email while she used a private server as secretary of state, Clinton seemed to be issuing "one set of rules for" herself and "a different set of rules for the rest of the State Department."