Replacing mitochondria could fix radiation damage and it can fix aging damage. This would help against cardiovascular disease and Alzheimers. There are early voluntary trials of mitochondria replacement by Mitrix Bio and Biotech Explorers that have started this year.

Researchers in the past decade have found that mitochondria don't just sit in cells, but in fact constantly transfer around the body. Everyday, hundreds of billions are transferred through the bloodstream, brain, heart, and other organs, in order to supplement cells in need. Many of these mobile mitochondria are encased in extracellular vesicles – what we term "Mitlets."

Mitlets are a "natural fountain of youth" within the body, used to balance and preserve healthy cellular energetics; an extraordinary evolutionary adaptation to increase survival and longevity of species.

Scaling Mitochondria harvesting and replacement and speeding regulatory approvals is work being done by the Healthspan Action Coalition. Nextbigfuture supports the Healthspan Action Coalition.

Every cell contains hundreds of mitochondria. They are vital organelles tightly integrated into many core cellular processes, and responsible for producing adenosine triphosphate, a chemical energy store molecule used to power the cell. Mitochondria become dysfunctional with age. This is an important contribution to degenerative aging. Cells will readily take up whole mitochondria from the surrounding tissue environment and make use of them. Thus it is possible to introduce large numbers of mitochondria harvested from cell cultures into a tissue in order to largely replace the native mitochondria. Provided that age-related mechanisms of damage and dysfunction that degrade the effectiveness of mitochondrial populations act slowly, then introducing young, functional mitochondria into an old individual should produce a lasting benefit. John G Cramer, a 90-year-old emeritus professor of physics at the University of Washington, has announced he will undergo a novel therapy that uses bioreactor-grown mitochondria, a technology developed by biotech startup Mitrix Bio.

Biotech Explorers, a startup based on research from Stanford and other major universities, is announcing the first-of-their-kind planned human trials of age reversal. These trials target a 130-year human lifespan, or an equivalent age reversal of 30 years, initially for astronauts and people with certain premature aging diseases. Early trials will use bioreactor-grown young mitochondria, transplanted into the body, to restore the decline in mitochondria… a primary cause of age