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IPFS News Link • Science, Medicine and Technology

Protein converts pancreatic cancer cells back into healthy cells

• http://www.gizmag.com, By Nick Lavars

 The method relies in the introduction of a protein called E47, which bonds with particular DNA sequences and reverts the cells back to their original state.

The study was a collaboration between researchers at the Sanford-Burnham Medical Research Institute, University of California San Diego and Purdue University. The scientists are hopeful that it could help combat the deadly disease in humans.

"For the first time, we have shown that over-expression of a single gene can reduce the tumor-promoting potential of pancreatic adenocarcinoma cells and reprogram them toward their original cell type," says Pamela Itkin-Ansari, adjunct professor at Sanford-Burnham and lead author of the study. "Thus, pancreatic cancer cells retain a genetic memory which we hope to exploit."


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