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IPFS News Link • Health and Physical Fitness

George Church indicates reversal of aging will be a reality within ten years

• http://www.nextbigfuture.com

Nextbigfuture suspects that this would likely be reversing aging in mice cells as a proof in principle. But maybe he does mean full reversal in humans.

In June 2016, Church indicated that first phase I aging reversal human trials could be in a year or two.

Fahy: Using your most favorable pathway for intervention, how long will it take before a human trial might be possible?

Church: I think it can happen very quickly. It may take years to get full approval, but it could take as little as a year to get approval for phase one trials. Trials of GDF11, myostatin, and others are already underway in animals, as are a large number of CRISPR trials. I think we'll be seeing the first human trials in a year or two.

Fahy: Can you say what those trials might be?

Church: I helped start a company called Editas that is aimed at CRISPR-based genome editing therapies in general. Some of those will be aimed at rare childhood diseases and others hopefully will be aimed at diseases of aging. We also have a company focused specifically on aging reversal that will be testing these therapies in animal and human models.


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